LIONNS-D2 Project - Production of T3S API, IMP and FDF

Cardiff University
Wales
Direct award
6 November 2025 to 31 January 2027

Production of Triiodothyronine sulphate (T3S) active pharmaceutical ingredient, investigational medicinal product, and finished drug formulation in blister packs. The work requires manufacturing to GMP standards using a validated route of synthesis to support a specific Phase 2b clinical trial for hypothyroid patients.

Open the official notice

Awarded value: Not published; No value in the notice
Published: 23 October 2025
Awarded: 22 October 2025; Ardena Holding NV
Contract length: 15 months; Ends 31 January 2027

What the contract covers

Contract manufacturing service

Contract manufacturing of active pharmaceutical ingredients and finished drug formulations for clinical trial research and development programmes.

Production of the Triiodothyronine sulphate (T3S) active pharmaceutical ingredient (API)
Production of the Triiodothyronine sulphate investigational medicinal product (IMP) for use in a Phase 2b clinical trial
Production of the finished drug formulation (FDF) in blister packs for hypothyroid patients with a specific genetic variation affecting thyroid hormone metabolism
Manufacture to GMP standards using a validated Route of Synthesis supported by existing preclinical and toxicology data

Terms and requirements

Contract type: Contract manufacturing service
Procedure: Direct award
Initial term: 15 months
Contract dates: 6 November 2025 to 31 January 2027
Certifications asked for: GMP
Lots: 1
Suitable for SMEs: Not stated
CPV codes: 33600000

Services in this contract

Aseptic compounding, specials and contract pharmaceutical manufacturingMain service£151k typicalManufacture of T3S API, IMP and blister-pack formulation for Phase 2b trial

Lifecycle

Published
23 October 2025
Contract awardedto Ardena Holding NV
22 October 2025
Contract starts
6 November 2025
Contract ends
31 January 2027

The buyer

Cardiff University

Type: Locked
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Recorded value: Locked
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Unlicensed medicines contracts, 24 months: Locked

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The supplier

Ardena Holding NV

Contracts won, 24 months: Locked
Buyers, 24 months: Locked
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Main buyers

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Cite this contract

Link: https://bidskim.com/tender/331016/lionns-d2-project-production-of-t3s-api-imp-and-fdf
Buyer reference: CU.1623.RR
Open contracting ID: ocds-h6vhtk-05d2df
Last checked: 5 November 2026

Cardiff University. LIONNS-D2 Project - Production of T3S API, IMP and FDF. Contract award, 23 October 2025. BidSkim, https://bidskim.com/tender/331016/lionns-d2-project-production-of-t3s-api-imp-and-fdf (accessed 5 November 2026).